Video Decision Aid Increases Advance Care Planning In Seniors With Chronic Kidney Disease

A randomized trial found higher advance care planning documentation after older adults with advanced kidney disease watched a video aid and recorded preferences.

Rare Brain Disorder Linked To Water Pollution Sources

A UK Biobank study found associations between PSP diagnoses and proximity to industrial facilities reporting water pollutants, but cannot prove causation.

Lyme Disease Vaccine Candidate Just Misses Its Mark In Late-Stage Trial

LB6V showed 73.2% efficacy in an evaluable analysis but missed a prespecified statistical threshold; a modified analysis narrowly passed.

Weakness And Mobility Loss In Aging Are Not Just Muscle Problems

A Lancet Healthy Longevity paper argues sarcopenia reflects changes across the motor system, not muscle loss alone, and calls for tests and trials.

AI Scribes Improved Note-Taking Time But Not Productivity, Study Finds

A study at a 14-hospital system found ambient AI scribes reduced clinicians’ note-active time and lengthened notes, with no productivity gains.

Women In Perimenopause Report More Anxiety Than Other Menopausal Groups

A review of 21 studies found higher odds of reported anxiety during perimenopause and after menopause than before it; the findings do not prove causation.

Moderna And Merck Say Their mRNA Cancer Vaccine Cut Death, Recurrence By 42%

Moderna and Merck report lower two-year recurrence-or-death risk with an mRNA vaccine plus Keytruda in a Phase 3 melanoma trial.

A 10-Year-old CNN Outperforms Frontier LLMs For Skin Cancer Diagnosis

A dermatologist’s test of 200 biopsied lesions found a fine-tuned Inception v3 CNN more often named the correct diagnosis than two frontier LLMs.

RSV Hospitalization May Be Taking A Surprising Mortality Toll, CDC Finds

A CDC analysis found 8.6% of adults hospitalized with RSV died in hospital or within 30 days of discharge across eight seasons.

Supplement Shows Promise For Improving Cancer-Related Cognitive Impairment

In a small uncontrolled study, breast cancer survivors reported better cognitive scores after eight weeks of oxaloacetate. A placebo-controlled trial is planned.